Hibernation Omics Analysis Workflows

Interactive visualization pipelines for seasonal metabolic reprogramming research.
From sequence alignment to multi-omics integration, specialized for torpor-arousal cycles.

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4. Spatial Transcriptomics

Spatial Transcriptomics

Tissue microenvironment & metabolic zonation

Hibernation Focus: Intestinal villus atrophy zones, BAT activation regions, hypothalamic nucleus metabolic gradients
1
Histology Alignment
H&E Overlay Villus/Crypt ID BayesSpace
2
Spatial Domain Identification
SVG Analysis SPARK Metabolic Gradients
3
Niche Interactions
Cell2location Mucus Layer Microbiome Host
4
Multi-modal Integration
MALDI-MSI Metabolite-Gene Liver Zonation
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Spatial Heatmap Spatial Scatter Niche Heatmap Dual Overlay